Putative phosphatidate phosphatase
WebFeature Type. ORF , Verified. Description. Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear/ER membrane association and activation of Pah1p, a phosphatidate phosphatase involved in the production of diacylglycerol DAG for lipid droplet biogenesis; phosphatase activity of the Nem1p-Spo7p complex is inhibited ... WebSep 2, 2024 · The Saccharomyces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phosphohydrolase, EC 3.1.3.4) …
Putative phosphatidate phosphatase
Did you know?
The enzyme phosphatidate phosphatase (PAP, EC 3.1.3.4) is a key regulatory enzyme in lipid metabolism, catalyzing the conversion of phosphatidate to diacylglycerol: a 1,2-diacylglycerol 3-phosphate + H2O $${\displaystyle \rightleftharpoons }$$ a 1,2-diacyl-sn-glycerol + phosphateThe reverse … See more Phosphatidate phosphatase regulates lipid metabolism in several ways. In short, it is a key player in controlling the overall flux of triacylglycerols to phospholipids and vice versa, also exerting control through the generation and … See more PAP belongs to the family of enzymes known as hydrolases, and more specifically to the hydrolases that act on phosphoric monoester bonds. This enzyme participates in 4 See more There are several different genes that code for phosphatidate phosphatases. They fall into one of two types (type I and type II), depending on their cellular localization and substrate specificity. Type I Type I … See more Lipin-1 deficiency in mice results in lipodystrophy, insulin resistance, and neuropathy. In humans, variations in Lipin-1 expression levels … See more Phosphatidate phosphatase is up-regulated by CDP-diacylglycerol, phosphatidylinositol (formed from reaction of CDP-diacylglycerol with inositol), and cardiolipin. It is down-regulated by sphingosine and dihydrosphingosine. This makes sense in the … See more The systematic name is diacylglycerol-3-phosphate phosphohydrolase. Other names in common use include: • phosphatidic … See more Human genes that encode phosphatidate phosphatases include: • PPAP2A (LPP1) – phosphatidic acid phosphatase type 2A See more WebPutative phosphatidate phosphatase, Germ cell guidance factor, Phosphatidic acid phosphatase type 2, Protein wunen, WUN_DROME UniProt Code History P91661, Q8MKU5, Q8WT60, Q9U9Y7, Q9V576
Webputative phosphatidate phosphatase. Gene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. LOC105560655 putative phosphatidate phosphatase [] Gene ID: 105560655, updated on 13-Feb-2024 ... WebJul 23, 2000 · Two cDNAs encoding putative phosphatidate phosphatases (PAPs) designated VuPAP-α and VuPAP-β were cloned in cowpea (Vigna unguic-ulata L.) leaves. The predicted proteins have six membrane ...
WebOct 13, 2006 · Gingras et al. (2005) identified PP4R3-beta as a protein that interacted with the protein phosphatase-4 catalytic subunit (PPP4C; 602035) in HEK293 cells. The deduced 764-amino acid PP4R3-beta shares 67% amino acid identity with PP4R3-alpha (SMEK1). It contains an N-terminal domain that is similar to the RAN ( 601179 )-binding domain of … WebPreparing publication...
WebFeb 21, 2024 · In this study, we characterized the MoPAH1 gene in M. oryzae, encoding a putative highly conserved phosphatidate phosphatase. The expression of MoPAH1 was up-regulated during plant infection. The MoPah1 protein is expressed at all developmental and infection stages, and is localized to the cytoplasm.
WebJan 27, 2003 · Expressed in embryonic gut in a pattern that guides germ cells towards mesoderm (initially in ... the social benefits of hydroelectric powerWebMar 17, 2016 · Background. Protein Phosphatase 1 (PP1) is an enzyme essential to cell viability in the malaria parasite Plasmodium falciparum (Pf). The activity of PP1 is regulated by the binding of regulatory subunits, of which there are up to 200 in humans, but only 3 have been so far reported for the parasite. the social biltmoreWebIn this study, we characterized the MoPAH1 gene in M. oryzae, encoding a putative highly conserved phosphatidate phosphatase. The expression of MoPAH1 was up-regulated … the social block apartmentsWebApr 13, 2024 · Keymessage The putative myristoylome of moss P. patens opens an avenue for studying myristoylation substrates in non-canonical model plants. A myristoylation signal was shown sufficient for membrane targeting and useful for membrane dynamics visualization during cell growth. Abstract N-myristoylation (MYR) is one form of lipid … myra school of business case studyWebAug 24, 2024 · In the filamentous fungus Sordaria macrospora (Sm), the STRIPAK complex is required for vegetative growth, fruiting-body development and hyphal fusion. The SmSTRIPAK core consists of the striatin homolog PRO11, the scaffolding subunit of phosphatase PP2A, SmPP2AA, and its catalytic subunit SmPP2Ac1. Among other … myra seafront suites and penthouses by lovWebThe gene encoding a putative phosphatidate phosphatase (PAP) from tolerant saline-alkali (TSA) Chlorella, ChPAP, was identified from a yeast cDNA library constructed from TSA Chlorella after a ... myra seafront suites \\u0026 penthouses by lovWebGiven these roles in phospholipid synthesis, we hypothesized that PA phosphatase was regulated in response to zinc status. In this work, we found that the expression of PAH1-encoded PA phosphatase was induced by zinc deficiency through a mechanism that involved interaction of the Zap1p zinc-responsive transcription factor with putative UAS … myra school of business unviersity