Iron-sulfur cluster-binding protein ykgf

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August undefined, 2024

WebFeb 1, 2024 · Iron-Sulfur (Fe-S) clusters are essential for life, as they are widely utilized in nearly every biochemical pathway. When bound to proteins, Fe-S clusters assist in catalysis, signal recognition, and energy transfer events, as well as additional cellular pathways including cellular respiration and DNA repair and replication. In Eukaryotes, Fe-S clusters … WebFeb 8, 2024 · Chestnut Hill, Mass. (2/8/2024) – Boston College chemists have developed a strategy to monitor the presence or absence of iron-sulfur clusters, which are essential to the function of diverse...

Iron-Sulfur Cluster Biosynthesis - RCSB: PDB-101

Webthan a [2Fe-2S] cluster. The site-directed mutation experi-ments suggest that the four cysteine residues are involved in the ligation of this [4Fe-4S] cluster. This iron-sulfur cluster has a unique feature, very high sensitivity to oxygen exposure, which has not been observed on other EPR-detectable iron-sulfur clusters in NDH-1/complex I. WebMar 24, 2009 · Protein Submitted name: Iron-sulfur cluster-binding protein Gene ykgF Organism Bacillus cereus (strain Q1) Status Unreviewed-Annotation score: Annotation … church of eugenia cooney

ykgF - Iron-sulfur electron transport protein

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) WebJul 31, 2024 · Lipoyl synthase (LIAS) is an iron–sulfur cluster protein and a member of the radical S-adenosylmethionine (SAM) superfamily that catalyzes the final step of lipoic acid biosynthesis. The enzyme contains two [4Fe–4S] centers (reducing and auxiliary clusters) that promote radical formation and sulfur transfer, respectively. WebIron-sulfur cluster proteins participate in the control of gene expression, oxygen/nitrogen sensing, control of labile iron pool and DNA damage recognition and repair. Their role in … church of eternal light

Iron-sulfur cluster biosynthesis

WebIron-sulfur proteins are involved in various biological electron transport processes, such as photosynthesis and cellular respiration, which require rapid electron transfer to sustain … WebBinding site: 111 [4Fe-4S] cluster 1 (UniProtKB ChEBI) PROSITE-ProRule annotation. Sequence: C: Binding site: 114 ... PTHR10849 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL 1 hit; PROSITE. View protein in PROSITE; PS00198 4FE4S_FER_1 2 hits; PS51379 4FE4S_FER_2 2 hits; Pfam. View protein in Pfam; churchoffemcWebOct 8, 2024 · show that thousands of novel binding sites for iron-sulfur (Fe-S) clusters and zinc ions can be identified ... sensing iron and oxygen [10-12], while Zn binding is … church of ezra ravenloft

"WebApr 22, 2024 · An iron–sulfur grip. In mammalian cells, iron homeostasis is regulated through iron regulatory proteins binding to iron-responsive mRNA elements. As part of … " - Iron-sulfur cluster-binding protein ykgf

Iron-sulfur cluster-binding protein ykgf

WebAbstract. Iron–sulfur clusters are ubiquitous and ancient prosthetic groups that are present in all kingdoms of life. They are flexible in terms of coordination and redox properties. The … WebIron–sulfur clusters are ubiquitous in modern biological systems, serving multiple purposes including protein structural stabilization, electron transfer, substrate binding and …

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WebIron-sulfur clusters are perfect for this task, since they form a unique delocalized system for storing an electron that may be tuned by the surrounding amino acids in a protein. Two types of clusters are particularly common: a square arrangement of two irons and two sulfurs, and a distorted cube composed of four irons and four sulfurs. WebDec 14, 2024 · Two forms of iron–sulfur clusters binding have been identified in pigeon MagR and showed different magnetic properties: [3Fe–4S]-MagR appears to be superparamagnetic and has saturation...

WebOct 19, 2024 · Our data indicate that the iron-sulfur cluster is critical for interaction of human Polε with DNA. Probably, abrogated DNA binding is responsible for the loss of both activities in hPolε CD.... WebNational Center for Biotechnology Information

WebAbstract Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene … WebThe proteins shown here are all part of one of the major systems found in bacteria, termed the ISC system. A similar system builds iron-sulfur clusters in our mitochondria. These …

Web2 days ago · Introduction. Iron is an essential trace element that functions as a cofactor in a wide variety of biological processes, such as oxygen delivery, ATP production, and DNA synthesis and repair, by binding to proteins (1, 2).However, excess iron is toxic owing to its ability to promote the generation of reactive oxygen species (3, 4).Ferroptosis (5), a type …

WebSearch Result : 6208 hits Entry KO len SW-score(margin) bits identity overlap best(all) ----- ----- asc:ASAC_0044 hypothetical protein K00782 400 1538 ( 1391) 356 0.587 390 <-> 3 clg:Calag_1048 hypothetical protein K00782 399 1513 ( 1389) 351 0.556 394 <-> 3 acia:SE86_01000 (Fe-S)-binding protein K00782 400 1505 ( 1155) 349 0.586 384 <-> 4 … dewalt saw repair near meWebIron-sulfur clusters have a remarkable facility for conversion and interconversion in both the free and protein-bound conditions, supporting the concept that they are modular structures. They also undergo ligand exchange reactions and oxidative degradation, both of which are biologically significant. churchoffemc kasumiWebGO:0051536 ! iron-sulfur cluster binding GO:0051539 ! 4 iron, 4 sulfur cluster binding GO:0055114 ! oxidation-reduction process GO:0003674 ! molecular function GO:0005575 ! … dewalt saw stand with wheelsWebJan 31, 2024 · Iron sulfur proteins (Fe-S) are ancient structures present in archaebacteria and are involved in central metabolic functions in these ancient organisms (Iwasaki, Archaea 2010:1, 2010). From an evolutionary perspective, Fe-S clusters originated early on during protein evolution; with the aid of an inducible and robust antioxidant defense system ... dewalt saw stand bracketsWebNov 5, 2024 · IscR (iron-sulfur cluster regulator) is an iron-dependent regulator of isc-suf genes and other genes with a role in iron metabolism. ... Gel-retardation assays showed the binding of regulatory proteins to individual promoters. Our results demonstrated that several promoters in a sense and antisense direction influenced isc-suf expression and ... dewalt saw kit cordlessWebJul 23, 2024 · When the iron salt is dissolved, adjust the volume to 10 mL ( see Note 7 ). 2. Fe dilution: 1 mM ammonium iron ( ii) sulfate ( (NH 4) 2 Fe (SO 4) 2 ·6H 2 O). Add 25 μL of … dewalt saw stand lowesIron–sulfur clusters are molecular ensembles of iron and sulfide. They are most often discussed in the context of the biological role for iron–sulfur proteins, which are pervasive. Many Fe–S clusters are known in the area of organometallic chemistry and as precursors to synthetic analogues of the biological clusters (see Figure). It is believed that the last universal common an… dewalt sawzall 20v cordless kit