How does phenytoin cause gingival hyperplasia

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August undefined, 2024

WebMay 11, 2014 · Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less ... WebThe most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing. [1]

Phenytoin as a risk factor in gingival hyperplasia - PubMed

WebMedically Induced Gingival Hyperplasia ANTICONVULSANTS. Although the association between phenytoin and gingival overgrowth is widely … WebIn addition to phenytoin, also lamotrigine, oxcarbazepine, and phenobarbital were associated with increased prevalence of gingival overgrowth. In the management of epileptic patients, dentists should take into account different drugs as possible causes for gingival overgrowth and warn for possible alternatives. Open Research shaolin temple images

Gingival Enlargement - AAOM

WebJun 7, 2024 · The differential diagnosis of gingival hyperplasia includes poor oral hygiene, medications like cyclosporine and phenytoin, systemic illnesses like sarcoidosis or Crohn’s disease, hematological disorders like AML, and genetic conditions. Patients can experience gingival hyperplasia because of leukemic infiltration into the gums. WebThere are several causes of gingival enlargement and they can be grouped into four categories: 1) inflammatory gingival enlargement, 2) medication-induced gingival enlargement, 3) hereditary gingival fibromatosis, and 4) systemic causes of gingival enlargement. Inflammatory Gingival Enlargement shaolin temple book of demons

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Phenytoin and gingival mucosa: A molecular investigation

WebApr 1, 2024 · Phenytoin is used to control seizures (convulsions), including tonic-clonic (grand mal) and psychomotor (temporal lobe) seizures, in the treatment of epilepsy. It is also used to prevent and treat seizures that occur during brain surgery. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. WebSep 19, 2024 · Phenytoin, cyclosporin, and nifedipine are the most common causes of gingival overgrowth, and phenytoin has the highest prevalence … shaolin temple legend of the heroWebJun 2, 2024 · Gingival health has altered physiology in many conditions ranging from local to systemic linked causes. Gingival enlargement or hyperplasia is not an uncommon oral health issue as it is usually symptomatic with bleeding, bad breath, and an unsightly puffed or inflamed appearance. Read the article to find out the causes, types, and management … shaolin temple decorations

"WebPhenytoin sodium is known to be the most common cause of gingival hyperplasia. 1,4 A minor degree of hyperplasia occurs quite commonly and this generally causes only … " - How does phenytoin cause gingival hyperplasia

How does phenytoin cause gingival hyperplasia

Phenytoin-Induced Gingival Overgrowth: A Review of the …

WebNational Center for Biotechnology Information WebKeppra can cause dizziness, fatigue and weakness. Phenytoin (Dilantin): Used for treatment of tonic-clonic seizures and complex partial seizures. Phenytoin will enter breast milk and cross the placenta. Common side effects include ataxia, hypotension, diplopia, nausea and gingival hyperplasia.

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WebMay 19, 2011 · Pathogenesis of phenytoin-induced gingival overgrowth. Several mechanisms are involved in the development of gingival overgrowth. Phenytoin induces a … WebThe most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by …

WebThe term “gingival hyperplasia” is inappropriate because enlargement does not result from an increase in the number of cells but rather an increase in extracellular tissue volume with an inflammatory infiltrate of predominantly B lymphocytes. 30 Histologically, in verapamil induced gingival enlargement there is highly vascular connective ... WebGingival hyperplasia is a condition when the gum tissue becomes enlarged and gingival cells increase in number. First documented in dental literature in 1939 as a side effect of phenytoin, this condition starts with a mild swelling or enlargement that, if left untreated, progresses rapidly.

WebPhenytoin can cause the platelet or white blood cell counts to drop, increasing the risk of bleeding or infection, respectively. Phenytoin also can cause anemia. ... Picture of Gingival Hyperplasia from Phenytoin. Gingival hyperplasia from phenytoin. Gingival hyperplasia can result in some patients who are taking the anti-seizure medication... WebSep 19, 2024 · Phenytoin (PHT, or 5,5-diphenylhydantoin), sodium valproate, phenobarbitone, vigabatrin, primidone, mephenytoin, and ethosuximide are some of the drugs that cause gingival hypertrophy. However, phenytoin is the anticonvulsant most associated with gingival enlargements. It is used to treat temporal lobe, tonic-clonic, and …

WebGingival hyperplasia was very common in patients taking PHT (16%-94% of patients). Alveolar bone loss occurred in patients taking carbamazepine or PHT. Patients taking valproate, carbamazepine or phenobarbital also had gingival hyperplasia. We found no published studies of newer-generation AEDs.

WebSep 26, 2024 · Gingival hyperplasia can happen due to various causes, including plaque buildup or oral inflammation, side effects from medication, and systemic conditions such as Crohn’s disease. Treating the underlying cause of … shaolin temple kung fuWebThere was a tendency for gingival hypertrophy to be associated with both increasing dosage of phenytoin per unit of body weight and the duration of phenytoin administration. All patients followed had a statistically significant progressive trend to increasing gingival hyperplasia with higher total and free phenytoin concentration. Publication types shaolin temple mapWebThe active drugs lamotrigine, oxcarbazepine, and phenobarbital were significantly associated with gingival overgrowth in 61%, 71%, and 53% of cases, respectively, and … shaolin temple lomitaWebCause‌s of gingival hyperplasia not caused by drugs include: Inflammation. If plaque builds up on your teeth because of poor hygiene, certain foods, or bacteria, it can lead to … pontardawe things to doWebSeveral distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of the main drugs associated … shaolin temple maplestoryWebJan 6, 2024 · Gingival hyperplasia is often a painful condition that can cause the following: Red and/or bleeding gums Bad breath Plaque buildup on teeth Tender/inflamed gums Pain This condition also negatively impacts your oral health standing. If left untreated, your gums can begin to fully cover your teeth, causing poor oral hygiene. pontardawe to neath bus serviceWebSep 26, 2024 · anti-seizure drugs, such as phenytoin. immunosuppressants, such as cyclosporine and tacrolimus. calcium channel blockers, such as nifedipine and … shaolin temple logo