WebMar 1, 2024 · Section snippets Results. In this work, metabolic models were reconstructed for CSCs and CCs of ten different tissues (AML, glioblastoma, lung, prostate, liver, ovary, breast, kidney, head and neck, and pancreatic cancers), by integrating gene expression data from ten individual datasets with the generic genome-scale metabolic model for human … WebNov 18, 2024 · Contribute to sysbiolux/rFASTCORMICS development by creating an account on GitHub. A tag already exists with the provided branch name. Many Git …

GitHub - sysbiolux/rFASTCORMICS

WebFASTGenomics – The platform for single-cell transcriptomics - FASTGenomics WebOct 1, 2024 · In total, SARS-COV-2-specific essential genes and gene pairs were predi cted by rFASTCORMICS- based lung models that can be targeted by 85 single repositionable drugs an d 52 drug combinations. The javascript programiz online

Drug Target Prediction Using Context-Specific Metabolic Models ...

WebBackground: Metabolic rewiring allows cancer cells to sustain high proliferation rates. Thus, targeting only the cancer-specific cellular metabolism will safeguard healthy tissues. … WebJan 25, 2016 · Author Summary Genome-wide association studies (GWAS) typically generate lists of trait- or disease-associated SNPs. Yet, such output sheds little light on the underlying molecular mechanisms and tools are needed to extract biological insight from the results at the SNP level. Pathway analysis tools integrate signals from multiple SNPs at … WebFASTCORE [15], rFASTCORMICS [7], INIT [5], and RegrEX [16] / or manually curated such as for E. coli [8], hepatocyte [17], and Zea mays [18]. These models are often used as scaffolds for the integration of omics data or more interesting to simulate the metabolic phenotypes of organisms, tissues, or cell lines. javascript print image from url